Online Submission

The JCRS submission is with the  web-based submission and peer review. To submit your manuscript online, go to

  • Prepare your manuscript and illustrations in the appropriate format, according to the instructions given below. Please also be sure that your paper conforms to the scientific and style instructions of the journal.
  • If you are unsure of your password, enter your e-mail address in the “Forget Password” box. If you have an account, a temporary password will be e-mailed to you to gain access to your account. If you do not have an account, you can create one for yourself in the system at the submission site by clicking on the “Register” button. Subsequently, to monitor the progress of your manuscript throughout the review process, log in to Manuscript Central periodically and check your Author Center.
  • All submissions are kept strictly confidential.


Editorial Policy

Every new manuscript is assigned a manuscript tracking number corresponding closely to the received date. To avoid confusion, authors should use the manuscript tracking number in all future correspondence with the editorial office. Manuscripts deemed suitable for the Journal of Chemical Reactivity and Synthesis will be sent out for peer review. Manuscripts deemed unsuitable for any reason will be either rejected or sent back to the authors for revision. The JCRS  is a peer-reviewed journal and as such takes the recommendations of selected reviewers very seriously; however, the final decision regarding the suitability of a submitted manuscript resides solely with the editor. All scientific results reported within a manuscript must be those of the submitting authors or be suitably referenced or acknowledged such that those responsible for the results are given proper credit for their work. Submission of a manuscript to the JCRS indicates that this work is unique to the best of the authors' knowledge and that this information has only been submitted to this journal. Failure to adhere to high ethical standards will result in rejection of the manuscript and could lead to an author being barred permanently from publishing in the JCRS.

Authors bear the sole responsibility for the contents of manuscripts and the accuracy of the data therein.

Manuscript Preparation

Manuscripts should be prepared using a modern word processing program, preferably MS Word. A single-column, double-spaced format should be used throughout the text. Manuscripts should be reasonably subdivided into sections and, if necessary, subsections. Please refer to any issue of this journal for examples. Twelve-point Times New Roman font should be used for all manuscripts. Greek letters and mathematical symbols (if any) should be typed in Symbol font; graphics for Greek letters and mathematical symbols should be avoided. The manuscripts will be compose of these sections : Keywords ( at least 4 words ) – Abstracts - Introduction – Experimental – results – conclussion – acknoledgmet ( if any) – references .

Drawings, graphs, and illustrations should be submitted in electronic format. All digital art must be saved as TIFF or EPS files. (Note that the following file formats are not acceptable for printing: JPG, GIF, ONG, PCX, PNG, XBM, Word, Excel.) Please save all images separately. Images should be flattened prior to submission (i.e. files should not contain layers). All line art should have a resolution yielding 600–1200 dpi. Grayscale and color figures must have a resolution yielding 300 dpi. (To ensure that your digital graphics are suitable for print purposes, please go to Rapid Inspector at: This free, stand-alone software application will help you to inspect and verify illustrations right on your computer.) Art should be created or scaled to the size intended for print; no enlargement or reduction should be necessary. Digital art files should be cropped to remove non-printing borders. Files should be checked carefully for any type, lines, or other elements outside the illustration that are not intended for print. Such elements should be removed before submission. Image orientation should be the same as intended for print.

Tables should be created with the table-formatting feature in a Word document, not as graphics. Each data point must be incorporated into its own table cell. All tables must be numbered with Arabic numerals (e.g., Table 1) in the order in which they are mentioned in the text. Each table must have a short title describing the content. All table columns should have an explanatory heading. Notes within tables (if any) should be denoted by consecutive, lowercase, superscripted letters. Tables must be saved separately. The duplication of data in figures and tables should be avoided. The tables should be formatted to fit a single- or double-column printed width. Tables should clearly present data without reference to the manuscript text.

Literature references are to be numbered consecutively in order of appearance of the reference in the text and are to be placed at the end of the manuscript under the center heading References. Reference numbers are to be placed in square brackets on the same line as the text. Authors are encouraged to include all pertinent references. All references should be compiled on a separate page at the end of the manuscript. Abbreviations of journal titles should conform to the practices of Chemical Abstracts Service Source Index (CASSI), though without italics or boldface, and periods or commas should not be used. Sample references follow.

Journal article:
[1] S. Khademi, S. Zahmatkesh, A. Aghili and R. Badri, Inter. J. Heterocycle. Chem. 9 (2019) 22-28.

[2] L.C.Y. Woo, V.G. Yuen, K.H. Thompson, J.H. McNeill  and  C. Orvig, J. Inorg. Biochem. 76 (1999) 251-259.

[3] Newkome, G. R.; Paudler, W. W. Contemporary Heterocyclic Chemistry; Wiley: New York, 1982.

Book with multiple contributors:
[4] Schneller S. W. In Comprehensive Heterocyclic Chemistry; Potts, K. T., Ed.; Pergamon Press: Oxford, 1984; Vol 5.

Patent citation (should include the Chemical Abstract reference):
[5] Van Schoor, A.; Schumann, W.; Lust, S.; Flemming, H. German Patent 1,141,487, 1962; Chem Abstr 1963, 58, 12470g.

References are the responsibility of the authors.

Nomenclature must conform to the recommendations set forth in the following sources: (1) Nomenclature of Organic Chemistry (IUPAC Blue Book), J. Rigaudy and S. P. Klesney, 1979 ed., Pergamon Press, Oxford; (2) Ring Systems Handbook, 2003 ed., Chemical Abstracts Service, 2540 Olentangy River Road, P.O. Box 3012, Columbus, OH 43210.


The experimental section should typically be located after the results and discussion section and should provide the reader with a clear and unambiguous description of the work reported. It should not be verbose, but should be sufficiently detailed that it is readily reproducible. The title of each experiment should include the chemical name of the compound and the assigned compound number. Either bold face Arabic or Roman numerals may be used for compound numbers; however, once one is chosen it must be used throughout the manuscript. At least one complete sentence per paragraph is encouraged but not required. Each previously unreported compound must be supported by adequate spectral data and elemental analyses for at least two elements agreeing with the theoretical value to within 0.4%. All elemental analytical data will be published. If suitable elemental analysis cannot be obtained, the authors should provide detailed reasons in the cover letter to the editor accompanying submission of the manuscript. Electronic copies of full spectral width NMR spectra (approximately -1 to 12 ppm) should be submitted along with the manuscript for compounds submitted without elemental analysis. Chemical names are preferred over chemical formulas and abbreviations in the discussion sections of the manuscript. Chemical formulas and limited use of abbreviations may be used in the experimental in place of chemical names. The following abbreviations, acronyms, and conventions may be used: g, mg, mL, L, mp, bp, tlc, hplc, gc, uv, ir, nmr, pmr, cmr, ms, hrms, lit, dec, mole, mmole, moles, mmoles, or mol, and mmol. The acronyms gc, uv, ir, nmr, pmr, cmr, ms, hrms may be either upper or lower case, but should be consistent throughout the manuscript. Other abbreviations are to be avoided, using in place of an abbreviation the complete word. All acronyms not listed above must be written out the first time it appears in the text. Extensive use of acronyms should be avoided. It is requested that simple punctuation be used in the experimental.

1-Benzamido-1,2,3,3a-tetrahydro-2-oxo-3-phenyl-1-azaazulene (9a). This compound was obtained as colorless needles (isopropyl alcohol), mp 179–180 °C; ir: NH 3200, CO 1725, 1675 cm-1; 1H nmr: δ 3.12 (br, 1H, 3a-H), 3.86 (br d, 1H, 3-H, J = 5.7 Hz), 5.24 (dd, 1H, 4-H, J = 3.0, 9.0 Hz), 5.44 (d, 1H, 8-H, J = 6.3 Hz), 6.1-6.5 (m, 3H, 5-, 6-, and 7-H), 7.2-7.9 (m, 10H, phenyl protons), 9.3 ppm (br s, 1H, NH); ms: m/z 342 (M+), 224 (M+-PhCHCO), 119 (PhNCO+), 105, 77. Anal. Calcd. for C22H18N2O2: C, 77.17; H, 5.30; N, 8.18. Found: C, 77.16; H, 5.28; N, 8.35.

1,2,3,3a-Tetrahydro-2-oxo-1-phenylacetylbenzamido-3-phenyl-1-azaazulene (10a). This compound was obtained as colorless prisms (isopropyl alcohol), mp 158–159 °C; ir: CO 1755, 1730, 1705 cm-1; 1H nmr: δ 2.86 (br, 1H, 3a-H), 3.82 (br d, 1H, 3-H, J = 5.4 Hz), 4.15, 4.37 (2d, each, 1H, -CH2-, J = 15.3 Hz), 5.25 (dd, 1H, 4-H, J = 3.2, 9.6 Hz), 5.44 (d, 1H, 8-H, J = 6.3 Hz), 6.0–6.7 (in, 3H, 5- 6-, and 7-H), 7.1-7.7 ppm (m, 15H, phenyl protons); ms: m/z 460 (M+), 341 (M+-PhCH2CO), 224 (hydrazone 1+), 119 (PhNCO+), 105, 77. Anal. Calcd. for C30H24N2O3: C, 78.24; H, 5.25; N, 5.97. Found: C, 78.23; H, 5.25; N, 6.38.