Original Paper
1. Cytotoxicity, Anti-microbial activity and molecular docking simulation of novel Bis-chalcones linked to tetrahydro-[1,2,4]triazolo[3,4-a] isoquinoline moiety

Nada S. Ibrahim; Elshimaa M. Eid; Huwaida M. E. Hassaneen; Hamdi M Hassaneen; Ahmed H. M Elwahy; Ismail A Abdelhamid

Volume 9, Issue 2 , Spring 2019, Pages 1-20

Abstract
  Novel series of bis(tetrahydro-[1,2,4]triazolo[3,4-a]isoquinolin-3-yl)-3-arylprop-2-en-1-one) derivatives were prepared and their structures were confirmed by several spectral tools. Chalcone 11 was selected for our studies as an example of the series. Molecular docking studies revealed that compound ...  Read More

Original Paper
2. Evaluation of 4-Amino-5-benzofuran-2-oyl-2-(4-methoxyphenyl)aminothiazole for antidiabetic applications: an in vitro and in vivo study

Priya Rani M; Akhila V. R; Krishnapriya, K. G; Rajasekharan, K. N

Volume 9, Issue 2 , Spring 2019, Pages 21-37

Abstract
  The aim of the present study is to investigate the in vitro and in vivo antidiabetic activity of 4-amino-5-benzofuran-2-oyl-2-(4-methoxyphenyl)aminothiazole. Toxicity and in vitro antidiabetic study of the compound was carried out in L6 cell lines. In vivo antidiabetic studies were carried out in alloxan ...  Read More

Original Paper
3. Salicylic acid an efficient organocatalyst for synthesis of coumarins

Rushikesh Mane; Pramod Kulkarnia

Volume 9, Issue 2 , Spring 2019, Pages 38-48

Abstract
  Various substituted coumarins were synthesized in high yield and purity by direct reaction of substituted phenol and β-keto esters in the presence of a catalytic amount of salicylic acid under solvent-free conditions. This method is simple, cost-effective, short reaction time, simple work-up procedure, ...  Read More

Original Paper
4. Diverse Chemical and Pharmacological Properties of Triazine Compounds

Mohammad Asif

Volume 9, Issue 2 , Spring 2019, Pages 49-79

Abstract
  The 1,3,5-triazine is the common triazine moiety. Triazines are weak bases and have much weaker resonance energy than benzene, so nucleophilic substitution is preferred to electrophilic substitution. Heterocyclic bearing triazines moieties, represent an interesting class of compounds possessing a wide ...  Read More

5. Study of structural and optical properties of anthocyanin- modified TiO2 for the purpose of photodegradation

Marzieh Ataie Dila; Azadeh Haghighat zadeh

Volume 9, Issue 2 , Spring 2019, Pages 80-100

Abstract
  In this research, dye – sensitization method was used to improve the photocatalytic activity of titanium dioxide dye using natural pigment of anthocyanin. Product morphology were studied by scanning electron microscopy (SEM) and phase identification using X-ray diffraction (XRD) analysis. Spectroscopic ...  Read More

6. Tributyl hexadecyl phosphonium bromide as a new and efficient catalyst for the one-pot synthesis of 3,4-dihydropyrimidinones/thiones via a three component condensation reactions

Rashid Badri; Leila Mohammadi; Ali Reza kiasat

Volume 9, Issue 2 , Spring 2019, Pages 101-107

Abstract
  3,4-Dihydropyrimidinones are an important class of heterocycles due to their pharmaceutical and therapeutic properties. The most efficient method for synthesis of these 3,4-dihydropyrimidinones, first reported by Biginelli, involves three component, one-pot condensation of a β-ketoester with an ...  Read More